Advanced Surfaces for Stem Cell Research by Ashutosh Tiwari, Bora Garipcan, Lokman Uzun

By Ashutosh Tiwari, Bora Garipcan, Lokman Uzun

The publication outlines first the significance of additional mobile Matrix (ECM), that's a traditional floor for many of cells. within the following chapters the impact of organic, chemical, mechanical, and actual houses of surfaces in micro and nano-scale on stem phone habit are mentioned together with the mechanotransduction. Biomimetic and bioinspired ways are highlighted for constructing microenvironment of a number of tissues, and floor engineering functions are mentioned in tissue engineering, regenerative drugs and diversified kind of biomaterials in quite a few chapters of the book.

This e-book brings jointly leading edge methodologies and techniques followed within the examine and improvement of Advanced Surfaces in Stem mobilephone Research. recognized world wide researchers planned topics including:

  • Extracellular matrix proteins for stem mobile fate
  • The superficial mechanical and actual houses of matrix microenvironment as stem telephone destiny regulator
  • Effects of mechanotransduction on stem telephone behavior
  • Modulation of stem cells habit via bioactive surfaces
  • Influence of managed micro and nanoengineered surfaces on stem telephone fate
  • Nanostructured polymeric surfaces for stem cells
  • Laser floor amendment concepts and stem cells applications
  • Plasma polymer deposition: a flexible instrument for stem mobile research
  • Application of bioreactor suggestion and modeling recommendations in bone regeneration and augmentation treatments
  • Substrates and surfaces for keep watch over of pluripotent stem cellphone destiny and function
  • Application of biopolymer-based, floor transformed units in transplant medication and tissue engineering
  • Silk as a common biopolymer for tissue engineering

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Extra resources for Advanced Surfaces for Stem Cell Research

Sample text

Et al. Matrix cross-linking forces tumor progression by enhancing integrin signaling. Cell 139, 891–906, 2009. 36. , et al. Extracellular-matrix tethering regulates stem-cell fate. Nat. Mater. 11, 642–9, 2012. 37. , et al. A role for matrix stiffness in the regulation of cardiac side population cell function. Am. J. Physiol. Heart. Circ. Physiol. 308, H990–7, 2015. 38. , et al. Substrate modulus directs neural stem cell behavior. Biophys. J. 95, 4426–38, 2008. 39. , Gullberg D. Integrins. Cell.

Structure and function of basement membranes. Exp. Biol. Med. (Maywood) 232, 1121–9, 2007. 71. J. Cytokine regulation of proliferation and cell adhesion are correlated events in human CD34+ hemopoietic progenitors. Blood 88, 1168–76, 1996. 72. , Salama A. The alpha4beta1 and alpha5beta1 integrins mediate engraftment of granulocytecolony-stimulating factor-mobilized human hematopoietic progenitor cells. Transfusion 45, 1192–200, 2005. 73. A. VLA-5 is expressed by mouse and human long-term repopulating hematopoietic cells and mediates adhesion to extracellular matrix protein fibronectin.

Biol. Chem. 279, 37726–33, 2004. K. Tetraspanin KAI1/CD82 suppresses invasion by inhibiting integrin-dependent cross-talk with c-Met receptor and Src kinases. Oncogene 25, 2367–78, 2006. , Kazlauskas A. Integrins enhance platelet-derived growth factor (PDGF)-dependent responses by altering the signal relay enzymes that are recruited to the PDGF beta receptor. J. Biol. Chem. 274, 19551–8, 1999. , et al. Epidermal growth factor receptor-dependent regulation of integrinmediated signaling and cell cycle entry in epithelial cells.

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